The following articles are supporting work published by members of the BirchBioMed Advisory Board and UBC R&D team at PubMed (U.S. National Library of Medicine, National Institutes of Health).
PUBLICATIONS
A Randomized, Double-Blind, Active- and Placebo-Controlled Trial Evaluating a Novel Topical Treatment for Keloid Scars.
By: Mark S. Nestor MD PhDa,b,c, Brian Berman MD PhDa,b, Daniel L. Fischer DOa, Haowei Han DOa, Anita Gade DOa, David Arnold DOa, Alec Lawson BAa
https://jddonline.com/articles/dermatology/S1545961621P0964X
J Tissue Eng Regen Med.
TGF-β1-activated type 2 dendritic cells promote wound healing and induce fibroblasts to express tenascin c following corneal full-thickness hydrogel transplantation.
By: Mölzer C, Shankar SP, Masalski V, Griffith M, Kuffová L, Forrester JV, et al. Epub 2019 Jul 25.
https://pubmed.ncbi.nlm.nih.gov/30938102/
J Tissue Eng Regen Med.
Activation of Dendritic Cells by Crosslinked Collagen Hydrogels (Artificial Corneas) Varies With Their Composition.
By: Mölzer C, Shankar SP, Griffith M, Islam MM, Forrester JV, Kuffová L.Mölzer C, et al. Epub 2019 Jul 18. https://pubmed.ncbi.nlm.nih.gov/31144475/
J Tissue Eng Regen Med.
January 31, 2018 NPJ Regen Med. Biomaterials-enabled Cornea Regeneration in Patients at High Risk for Rejection of Donor Tissue Transplantation. By: Islam MM, Buznyk O, Reddy JC, Pasyechnikova N, Alarcon EI, Hayes S, Lewis P, Fagerholm P, He C, Iakymenko S, Liu W, Meek KM, Sangwan VS, Griffith M.Islam MM, et al.
https://pubmed.ncbi.nlm.nih.gov/29423280/
Acta Biomaterialia.
Short peptide analogs as alternatives to collagen in pro-regenerative corneal implants.
By: Jangamreddy JR, Haagdorens MKC, Mirazul Islam M, Lewis P, Samanta A, Fagerholm P, Liszka A, Ljunggren MK, Buznyk O, Alarcon EI, Zakaria N, Meek KM, Griffith M.Jangamreddy JR, et al. Epub 2018 Jan 31.
https://pubmed.ncbi.nlm.nih.gov/29355715/
J Cell Physiol.
Increased expression of PD-L1 and PD-L2 in dermal fibroblasts from alopecia areata mice.
By: Li Y, Kilani RT, Pakyari M, Leung G, Nabai L, Ghahary A. Epub 2017 Sep 4.
https://www.ncbi.nlm.nih.gov/pubmed/28777458
Cell Transplant. IDO-expressing Fibroblasts Suppress the Development of Imiquimod-induced Psoriasis-like Dermatitis.
By: Elizei SS, Pakyari M, Ghoreishi M, Kilani R, Mahmoudi S, Ghahary A.
Epub 2018 May 14.
https://www.ncbi.nlm.nih.gov/pubmed/29759005
Journal of Pharmaceutical Sciences The Safety and Tolerability of Topically Delivered Kynurenic Acid in Humans: A Phase 1 Randomized Double-Blind Clinical Trial.
By: Papp A, Hartwell R, Evans M, Ghahary A. https://www.sciencedirect.com/science/article/pii/S0022354918300662 Epub 2018 Feb 6. https://www.ncbi.nlm.nih.gov/pubmed/29421218
Tissue Eng Part A. Evaluation of Detergent-Free and Detergent-Based Methods for Decellularization of Murine Skin.
By: Farrokhi A, Pakyari M, Nabai L, Pourghadiri A, Hartwell R, Jalili R, Ghahary A.
Epub 2018 Apr 12.
https://www.ncbi.nlm.nih.gov/pubmed/29303417
Cell Transplant.
Fibroblast cell-based therapy prevents induction of alopecia areata in an experimental model.
By: Jalili RB, Kilani RT, Li Y, Khosravi-Maharlooie M, Nabai L, Wang EHC, McElwee KJ, Ghahary A.
Epub 2018 Jun 5.
https://www.ncbi.nlm.nih.gov/pubmed/29871523
Clin Immunol. Intraperitoneal injection of IDO-expressing dermal fibroblasts improves the allograft survival.
By: Khosravi-Maharlooei M1, Pakyari M, Jalili RB, Kilani RT, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/27989895
J Cell Biochem. Keratinocyte-Releasable Factors Stimulate the Expression of Granulocyte Colony-Stimulating Factor in Human Dermal Fibroblasts.
By: Carr MJ, Li Y, Rezakhanlou AM, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/?term=27340768
J Burn Care Res.
Therapeutic Use of Stem Cells in Treatment of Burn Injuries.
By: Cheng JZ, Farrokhi A, Ghahary A, Jalili RB
https://www.ncbi.nlm.nih.gov/pubmed/?term=28486306
Molecular and Cellular Biochemistry. Kynurenic acid downregulates IL-17/1L-23 axis in vitro.
By: Salimi Elizei S, Poormasjedi-Meibod MS, Wang X, Kheirandish M, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/?term=28285360
J Cell Physiol. Increased expression of PD-L1 and PD-L2 in dermal fibroblasts from alopecia areata mice.
By: Li Y, Kilani RT, Pakyari M, Leung G, Nabai L, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/?term=28777458
Methods Mol Biol. Hypertrophic Scarring in the Rabbit Ear: A Practical Model for Studying Dermal Fibrosis.
By: Nabai L, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/?term=28836196
J Cell Physiol. Increased expression of PD-L1 and PD-L2 in dermal fibroblasts from alopecia areata mice.
By: Li Y, Kilani RT, Pakyari M, Leung G, Nabai L, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/?term=28777458
Adv. Healthc Mater. An Advanced Multifunctional Hydrogel-Based Dressing for Wound Monitoring and Drug Delivery.
By: Mirani B, Pagan E, Currie B, Siddiqui MA, Hosseinzadeh R, Mostafalu P, Zhang YS, Ghahary A, Akbari M
https://www.ncbi.nlm.nih.gov/pubmed/?term=28944601
J Cell Physiol
IDO-Expressing Fibroblasts Protect Islet beta Cells from Immunological Attack and Reverse Hyperglycemia in Non-Obese Diabetic Mice
By: Zhang Y, Jalili RB, Kilani RT, Elizei SS, Farrokhi A, Khosravi-Maharlooei M, Warnock GL, Ao Z, Marzban L, Ghahary
https://www.ncbi.nlm.nih.gov/pubmed/26743772
PLoS One
Fibroblast Cell-Based Therapy for Experimental Autoimmune Diabetes
By: Jalili RB, Zhang Y, Hosseini-Tabatabaei A, Kilani RT, Khosravi Maharlooei M, Li Y, Salimi Elizei S, Warnock GL, Ghahary
https://www.ncbi.nlm.nih.gov/pubmed/26765526
Immunology
Tolerogenic Effect of Mouse Fibroblasts on Dendritic Cells
By: Khosravi-Maharlooei M, Pakyari M, Jalili RB, Salimi-Elizei S, Lai JC, Poormasjedi-Meibod M, Kilani RT, Dutz J, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/26789277
J Biomed Mater Res A.
Development of a nanofibrous wound dressing with an antifibrogenic properties in vitro and in vivo model.
By: Poormasjedi-Meibod MS, Salimi Elizei SS, Pakyari M, Jackson JK, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/27144507
J Cell Physiol
Kynurenine Modulates MMP-1 and Type-I Collagen Expression Via Aryl Hydrocarbon Receptor Activation in Dermal Fibroblasts. By: Poormasjedi-Meibod MS, Salimi Elizei SS, Leung V, Baradar Jalili R, Ko F, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/26992058
Wound Repair Regen
Effects of kynurenine on CD3+ and macrophages in wound healing
By: Salimi Elizei S, Poormasjedi-Meibod MS, Li Y, Baradar Jalili R, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/25532592
Transplantation
Immunoprotection and Functional Improvement of Allogeneic Islets in Diabetic Mice, Using a Stable Indoleamine 2,3-Dioxygenase Producing Scaffold
By: Hosseini-Tabatabaei A, Jalili RB, Khosravi-Maharlooei M, Hartwell R, Kilani RT, Zhang Y, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/25769070
Immunobiology
IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells
By: Curran TA, Jalili RB, Farrokhi A, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/23891282
J Invest Dermatol
Kynurenine increases matrix metalloproteinase-1 and -3 expression in cultured dermal fibroblasts and improves scarring in vivo
By: Li Y, Kilani RT, Rahmani-Neishaboor E, Jalili RB, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/23877570
PLoS One
Anti-scarring properties of different tryptophan derivatives
By: Poormasjedi-Meibod MS, Hartwell R, Kilani RT, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/24637853
Wound Repair Regen
Topical application of a film-forming emulgel dressing that controls the release of stratifin and acetylsalicylic acid and improves/prevents hypertrophic scarring
By: Rahmani-Neishaboor E, Jallili R, Hartwell R, Leung V, Carr N, Ghahary A
https://www.ncbi.nlm.nih.gov/pubmed/23126516
J Cell Physiol
MAP kinase mediates silica-induced fibrotic nodule formation and collagen accumulation in fibroblasts
By: Li Y, Kilani RT, Hartwell R, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/21437902
J Invest Dermatol
Application of an indoleamine 2,3-dioxygenase-expressing skin substitute improves scar formation in a fibrotic animal model
By: Chavez-Munoz C, Hartwell R, Jalili RB, Carr M, Kilani RT, Jafarnejad SM, Rahmani-Neishabour E, Forouzandeh F, Boyce ST, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/22297642
J Cell Biochem
SPARC/SFN interaction, suppresses type I collagen in dermal fibroblasts
By: Chavez-Muñoz C, Hartwell R, Jalili RB, Jafarnejad SM, Lai A, Nabai L, Ghaffari A, Hojabrpour P, Kanaan N, Duronio V, Guns E, Cherkasov A, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/22422640
Diabetes
Local expression of indoleamine 2,3 dioxygenase in syngeneic fibroblasts significantly prolongs survival of an engineered three-dimensional islet allograft
By: Jalili RB, Forouzandeh F, Rezakhanlou AM, Hartwell R, Medina A, Warnock GL, Larijani B, Ghahary A.
https://www.ncbi.nlm.nih.gov/pubmed/20522587
